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Product ID: PURPT5
Pure Encapsulations - Petadolex® (Butterbur), 50 capsules Discounts Apply !
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Pure Encapsulations - Petadolex® (Butterbur), 50 capsules

Petadolex® is a herbal supplement made by Pure Encapsulations, manufacturers of hypo allergenic nutrition supplements. Every batch of finished products are tested and certified by independent laboratories. All products are manufactured under conditions similar to those employed in making pharmaceutical grade drugs and complies with the FDA GMP guidelines. More Information on the Manufacturing and Quality Control of this supplement.

About Petadolex®:

*Butterbur is a perennial shrub with a 2,000-year history of traditional use. In the last twenty-five years, it has been trusted extensively throughout Europe by neurologists and other health professionals.

Petadolex®, a patented form of butterbur extracted from the root and standardized to contain a minimum of 15% petasin and isopetasin, has been studied for healthy cranial vessel support. Petasin-containing extracts of butterbur may also help to maintain healthy histamine and cytokine release.

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Active Ingredients:

petasin and isopetasin

Petadolex is standardized to contain at least 7.5 mg petasins per 50 mg and is processed to remove pyrrolizidine alkaloids.

Clinical Studies:

In one clinical trial with 60 participants, Petadolex showed the potential to support cranial vessel comfort and was well tolerated. After a twelve-week period, almost eighty percent of participants supplementing with Petadolex indicated a supportive effect. In part, the mechanism for this action may involve a supportive spasmolytic effect on smooth muscle in cranial blood vessels.

A second study with 229 individuals indicated similar positive results. In this trial, optimal dosing of Petadolex provided significant support compared to placebo within one month. After three months, over seventy percent of individuals experienced a positive outcome.

A petasin-containing butterbur leaf extract has been shown to maintain proper histamine and cytokine release without sedative effects. In two clinical trials, butterbur maintained healthy nasal histamine release and leukotriene activity, supporting both subjective and objective parameters.


Petadolex® provides high capacity support for healthy cranial blood vessel function. Butterbur may also promote immune function by maintaining healthy histamine and cytokine release.


Grossmann M, et al. An extract of Petasites hybridus is effective in the prophylaxis of migraine. Int J Clin Pharmacol Ther 2000 Sep;38(9):430-5.

Ingredients and Dosage:

each softgel capsule contains:
butterbur (Petasites hybridus) extract (28-44:1) (root) 50 mg.
(standardized to contain 7.5 mg of petasin and isopetasin)
other ingredients: riboflavin, glycerol, gelatin, sorbitol

Precautions/Side Effects:

Do not use if you are pregnant
Do not give to children
Do not use if you suffer from decreased gastrintestinal or geritourinary motility.
May cause irreversible liver damage in some persons.
May cause nausea, vomiting, anorexia, abdominal pain, constipation, shortness of breath.


2–3 capsules per day, in divided doses, with meals.

* These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. See Disclaimer

Petadolex® is a trademark of Weber & Weber. Manufactured for Pure Encapsulations, Inc. by Weber & Weber. Product of Germany.

Product Specifications and More Information:

Herbal Medicine Infocenter at


We generally ship within 5 business days. Please refer to our shipping policies for information about estimated shipping time and your options.

List Price: $65.40
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