l-Carnosine is a nutritional supplement made by Pure Encapsulations, manufacturers of hypo allergenic nutrition supplements. Every batch of finished products are tested and certified by independent laboratories. All products are manufactured under conditions similar to those employed in making pharmaceutical grade drugs and complies with the FDA GMP guidelines. More Information on the Manufacturing and Quality Control of this supplement.
*l-Carnosine (beta-alanyl-L-histidine) occurs naturally in the body's muscle and nervous tissues and is formed by the amino acids alanine and histidine. Levels of this dipeptide can decline with age. It is a water-soluble antioxidant with well-documented free-radical scavenging activity and is believed to promote cell health and cell longevity.
The primary function of l-carnosine appears to involve mediating the interaction between proteins and sugars. In vitro, it helps to protect proteins from the formation of advanced glycosylation end-products. These end-products are formed when aldehydes (such as aldose and ketose sugars) and lipid peroxidation by-products bind to vital proteins and compromise their function. l-Carnosine plays a role in protecting DNA from acetaldehyde and formaldehyde. Glycoaldehyde inactivation of superoxide dismutase also appears to be moderated by carnosine. l-Carnosine may help to maintain healthy peptide metabolism in the brain and its membrane-stabilizing properties support healthy lactate dehydrogenase activity of cardiovascular cells. The concentration of l-carnosine in muscle may prove to be an important factor in high-intensity exercise performance based on a recent human study.
l-Carnosine provides unique protective mechanisms in the body to maintain healthy protein and cellular function in various tissues. Supplementation may support optimal levels of l-carnosine, which can naturally decline with age.
Hipkiss AR, Brownson C, Carrier MJ. Carnosine, the anti-ageing, anti- oxidant dipeptide, may react with protein carbonyl groups. Mech Ageing Dev 2001 Sep 15;122(13):1431-45.
Ingredients and Dosage:
each vegetable capsule contains:
l-carnosine (beta-alanyl-L- histidine) 500 mg.
Not to be taken by pregnant or lactating women.
1–3 capsules per day, in divided doses, between meals.
* These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. See Disclaimer
Product Specifications and More Information: http://specialgifts.com/health/Resources/ProdInfo/default.htm
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