Indole-3-Carbinol is a specialty nutrition supplement made by Pure Encapsulations, manufacturers
of hypo allergenic nutrition supplements. Every batch of finished products
are tested and certified by independent laboratories. All products are
manufactured under conditions similar to those employed in making
pharmaceutical grade drugs and complies with the FDA GMP guidelines.
More Information on the Manufacturing and Quality Control of this supplement.
Indole-3-Carbinol (I3C) is a phytochemical naturally occurring in
cruciferous vegetables. Once ingested, stomach acid converts I3C to various
active metabolites including diindolylmethane (DIM), which are absorbed into
In nature, indole-3-carbinol can be found in cruciferous vegetables such
as broccoli, brussels sprouts, cabbage, bok choy, cauliflower, and kale.
Indole-3-Carbinol in supplement form is synthetically produced.
Indole-3-carbinol has been shown to promote healthy phase I cytochrome
P450 detoxification enzymes and phase II detoxification enzymes such as
glutathione S-transferase (GST). This enhances the liver’s ability to
process and eliminate harmful compounds. It has also been reported to act as
a scavenger of free radicals.
Additionally, indole-3-carbinol is believed to have other mechanisms
contributing to healthy cellular support. A placebo-controlled trial
indicated that I3C supports cervical cell health.*
Indole-3-carbinol, the powerful phytochemical found in cruciferous
vegetables, provides support for healthy breast and cervical cells.
Ingredients and Dosage:
each vegetable capsule contains:
indole-3-carbinol 400 mg.
(hypo-allergenic plant fiber added to complete capsule volume requirement)
Potential Side Effects Or Precautions
This formula requires refrigeration.
Not to be taken by pregnant and lactating women.
Should be avoided by those sensitive to cruciferous vegetables.
Potential Drug Interactions
The conversion of I3C to its active metabolites requires stomach acid.
Therefore, antacids, H2 blockers, and proton-pump inhibitors may impede its
1–2 capsules per day, in divided doses, with meals.
* These statements have not been evaluated by the Food & Drug Administration.
This product is not intended to diagnose, treat, cure or prevent any disease.
Vitamins and Nutrition Infocenter at 1stholistic.com
Vitamins Knowledgebase at 1stholistic.com
Product Specifications and More Information:
We generally ship within 5 business days. Please refer to our shipping policies for information about estimated
shipping time and your options.
1 bottle contains: 400 mg., 120 capsules
Also Available in:
400 mg., 60 capsules/bottle
200 mg., 120 capsules/bottle
200 mg., 60 capsules/bottle
To buy this item, click on the button marked "add to