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A.I. Formula®

What Is A.I. Formula?

A.I. Formula is a broad spectrum, synergistic combination of concentrated extracts which inhibit the discharge of histamine from activated mast cells or basophils and maintain healthy leukotriene and thromboxane production.*

Uses For A.I. Formula

• A.I. Formula offers a safe and natural way to regulate histamine production and other immune modulators, thus moderating the inflammatory response at the cellular level.*

• Quercetin inhibits the synthesis of enzymes necessary for the release and degranulation of histamine.*

• Bromelain inhibits the production of kinins and fibrin, compounds that promote the inflammatory process.*

• Curcuma longa, or turmeric, maintains healthy histamine release and immune cell response.*

• Ginger moderates leukotriene and thromboxane synthesis, important mechanisms for cellular and tissue support.*

The Source of A.I. Formula

This formula contains: bromelain (2400 gdu/gram), a proteolytic enzyme from the stem of the pineapple plant; Curcuma longa(turmeric) extract standardized to contain 97% curcuminoids; quercetin, which is primarily derived from the Brazilian botanical dimophandra; ginger extract ( Zingiber officinale) (root) (standardized to contain 5% gingerols); vitamin C (ascorbyl palmitate) derived from corn dextrose fermentation.

Potential Side Effects Or Precautions in Using A.I. Formula

If pregnant or lactating, consult your physician before taking this product. A.I. Formula contains Curcuma longa, which is not recommended for individuals with gallstones.

Potential Drug Interactions

A.I. Formula contains bromelain and ginger, which should not be taken with blood thinning medications due to potential or theoretical interactions.

Ingredients and Dosage

A.I. Formula®

each vegetable capsule contains quercetin- 250 mg.

Curcuma longa (turmeric) extract - 150 mg. (standardized to contain 97% curcuminoids)

bromelain (2,400 gdu/gram) - 200 mg.

ginger (Zingiber officinale) extract - 100 mg. (standardized to contain 5% gingerols)

vitamin C (as ascorbyl palmitate) - 14 mg.

Recommended Dosage:

2–6 capsules per day, in divided doses, between meals.

References:

1. Tordera M, Ferrandiz ML, Alcaraz MJ. Influence of anti-inflammatory flavonoids on degranulation and arachidonic acid release in rat neutrophils. Z Naturforsch [C] 1994 Mar;49(3-4):235-240.

2. Mascolo N, Pinto A, Capasso F. Flavonoids, leucocyte migration and eicosanoids. J Pharm Pharmacol 1988 Apr;40(4):293-295.

3. Gu ZL, Xie ML, Qian ZN. Effect of quercetin on chemiluminescence of human platelets induced by by arachidonic acid. Zhongguo Yao Li Xue Bao 1993 May;14(3):263-5.

4. Sreejayan; Rao MN. Nitric oxide scavenging by curcuminoids. J Pharm Pharmacol 1997 Jan;49(1):105-7.

5. Srivastava R. Inhibition of neutrophil response by curcumin. Agents Actions 1989 Nov;28(3-4):298-303.

6. Srivastava R; Srimal RC. Modification of certain inflammation-induced biochemical changes. Indian J Med Res 1985 Feb;81:215-23.

7. Srivastava KC, Mustafa T. Ginger (Zingiber officinale) in rheumatism and musculoskeletal disorder. Med Hypotheses 1992 Dec;39(4):342-8.

8. Kumakura S, Yamashita M, Tsurufuji S. Effect of bromelain on kaolininduced inflammation in rats. Eur J Pharmacol 1988 Jun 10;150(3):295-301.

9. Ako H, Cheung AH, Matsuura PK. Isolation of a fibrinolysis enzyme activator from commercial Bromelain. Arch Int Pharmacodyn Ther 1981

10. Vellini M, Desideri D, Milanese A, Omini C, Daffonchio L, Hernandez A, Brunelli G. Possible involvement of eicosanoids in the pharmacological action of bromelain. Arzneimittelforschung 1986;36(1):110-112.

11. Healthnotes Clinical Essentials. Copyright 2004. Healthnotes, Inc.

*This is a statement of nutritional support. This statement has not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

This information is for educational purposes only. Consult your physician for any health problems.

Source: Product Information Sheet from Pure Encapsulations

Manufacturers continually change product specifications. While we try our best to keep product descriptions up to date, they do not necessarily reflect the latest information available from the manufacturer. We are not responsible for incorrect or outdated product descriptions and/or images.

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